ea0084op-04-20 | Oral Session 4: Basic 1 | ETA2022
de Assis Leonardo
, Harder Lisbeth
, Thalles Lacerda Jose
, Parsons Rex
, Kaehler Meike
, Cascorbi Ingolf
, Nagel Inga
, Rawashdeh Oliver
, Mittag Jens
, Oster Henrik
Cellular 24-hour rhythms depend on transcriptional programs controlled by a set of circadian clock genes/proteins. Systemic factors like humoral and neuronal signals, oscillations in body temperature, and food intake align physiological circadian rhythms with external time. Thyroid hormones (THs) are major regulators of circadian clock target processes such as energy metabolism, but little is known about how fluctuations in TH levels affect the circadian coordination of tissue...